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Bacterial probiotics ( Lactobacillus/Lactiplantibacillus spp.) and probiotic yeasts ( Saccharomyces boulardii ) are capable of secreting organic acids (lactic acid, acetic acid, a variety of short-chain fatty acids), fatty acids (medium-chain fatty acids, like capric acid), and bacteriocin-like peptides and other small molecules that can suppress adhesion, hyphal transition, biofilm formation, and planktonic growth of Candida in vitro (Murzyn et al., 2010

This defense lowers the possibility of harm to lipids, proteins, and DNA while also assisting in the preservation of cellular integrity (1)

Manta et al., 2019)

Previous research showed immunosuppression in MM patients, manifested by increased CD8+ T cell exhaustion marker levels, hindering immunotherapy efficacy (60)