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Nez-Nevrez K, Lpez-Betancourt A, Cisneros-Prez V, et al.Relationship Between Weight and Severity of Fibromyalgia

41 Many factors that normally stimulate ET-1 synthesis, (for example, thrombin and AT-II) also cause the release of vasodilators, such as prostacyclin (PGI 2 ) and/or NO, which oppose the vasoconstricting function of ET-1