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The stage of pubertal development (I-V period) was assessed according to Tanner staging criteria, with Tanner II as the hallmark of puberty initiation

Preferably, the flush is anoxic (without molecular oxygen), to reduce oxidation

For example, CuO nanomaterials affect organs such as the kidney, liver, and spleen and can reduce the antioxidant response at the plasma level by enhancing malondialdehyde content