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Our histological outcomes support this conclusion, as well

Value and Efficiency High Value with Low Lifecycle Costs Tiered model range helps to increase ROI and align with customer budgets All In standard features provide exceptional value Reduced inventory costs with same seal kit used on multiple size ranges: DN40-DN65 (1.5-3.0) and DN80-DN100 (4.0) Reduced CIP losses improve cost savings Low air consumption and air supply requirements Long housing ports ease manifold building Integrated shaft seal flush reduces need for external piping Replacement insert available to easily upgrade existing installations Reliable Performance Optimized Operation and Control Fully balanced design helps to prevent hydraulic blocking, withstand pressure spikes, and enables flexible flow direction without slamming Light overall weight helps support handling without lifting tools Slim stainless actuator is fully enclosed to prevent fluid ingress Range of control units and bus communication for automated operation No compressed air needed for removal and servicing Cleanability and Hygienic Design Advanced Sanitary Features Designed to the latest hygienic standards Standard cavity spray cleaning Extensive cleaning of product contact seals Valve Feature Comparison D4 Valve Key Features Radial seal design minimizes product loss and enhances cleanliness Choice of seat-lifting (SL) or non-seat-lifting (NSL) actuators Hazardous-rated options (ATEX Zone 1 or 2) DA4 Valve Key Features Flushing for upper/lower shaft seals and balancer Metal orifices reduce CIP fluid consumption Insert upgrade compatible with DA3+ housing Shared Features in D4 & DA4 Open yoke enables leak detection and reduces heat transfer Bolted flange for secure insert connection Long ports for streamlined manifold assembly Two standardized seal kit sizes for all models Fully integrated position sensors No compressed air needed for servicing Balanced shaft design eliminates water hammer and supports dual flow direction Reduced chemical and cleaning fluid losses Large separation cavity drain port prevents cross-contamination Flush cavity spray connection for enhanced cleaning Lightweight valve body for easier handling Actuator Warranty & Reliability The actuator supplied with this valve is covered by a 5-year actuator warranty, or up to 1 million actuations, whichever comes first

doi: 10.1182/blood-2007-05-091256