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Oxidative stress plays a crucial role in the development of age-related diseases including arthritis, diabetes, dementia, cancer, atherosclerosis, vascular diseases, obesity, osteoporosis, and metabolic syndromes (Tan et al., 2015a

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for example, N -acetylcysteine (NAC) in preadipocytes reduces adipogenesis [27]

WT or mutated Mettl9 -FLAG sequences were synthetised as dsDNA (see Supplementary Data File 4) harbouring homology arms to the digested XhoI-NotI pyCAG-hygromycin vector