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Genetic polymorphisms of NOD2 and ATG16L1 in different types of digestive tract inflammation

The integrated optical density (IOD) of the immunohistochemical images was quantified using ImageJ software

Outcome measures The primary outcome was the effect of KD on clinical phenotypes (epilepsy, muscle involvement, tonus dysregulation (muscular hyper- or hypotonia), movement disorders, developmental delay and intellectual disability (DD/ID), other individual signs and symptoms) and the occurrence of adverse events (AEs)

CXCR3, CXCR4, and CXCR5 enhance Th1 cells, lymphocytes, B cells, and T follicular helper (Tfh) cells into joint, respectively (100, 103)