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Moreover, an elevated Bax/Bcl-2 ratio is considered a critical factor in the degenerative pathology of dopaminergic neurons

Neuroprotective Effects of Thymoquinone in Acrylamide-Induced Peripheral Nervous System Toxicity Through MAPKinase and Apoptosis Pathways in Rat

Under oxidative stress, high levels of superoxide can induce compounds including iron (4Fe-4S) clusters, heme, and ferritin to release Fe 2+ , which causes ferroptosis through Fenton and HaberWeiss reactions