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In addition, our data suggest that the GSH reduction correlate with the severity of the COVID-19 disease

For instance, Salvianolic acid B was shown to attenuate paraquat-induced pulmonary fibrosis by restoring the Nrf2/NOX4 redox balance, where Nrf2 activation suppressed NOX4 expression and downstream TGF-1/Smad3 signaling ( S

While its traditional use and numerous clinical studies indicate relative safety at typical therapeutic doses [228], emerging data call for a more nuanced evaluation of potential risks