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Downregulating MYCN in IMR-5/75 decreased caspase activation for both treatments, while inducing MYCN expression in SH-SY5Y/MYCN increased caspase activation, although the differences were not statistically significant ( Figure 4D )

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Since recognition of the connection between inadequate folate supply and neural tube defects 9,10,11 , FA has been added in many countries to a staple in the diet through mandatory fortification programs, usually of cereals or grains