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Surf Interfaces 19:100437

doi: 10.3389/fendo.2023.1294406 Received 14 September 2023 Accepted 14 December 2023 Published 11 January 2024 Volume 14 - 2023 Edited by Senthilkumar Palaniappan, Karpagam Academy of Higher Education, India Reviewed by Arnab Banerjee, Birla Institute of Technology and Science, India Sanaz Alaeejahromi, Shiraz University of Medical Sciences, Iran Updates Copyright 2024 Malik, Saeed, Saleem, Khan, Khan and Akhtar

Abstract Glioblastoma (GBM) is the most aggressive and lethal form of primary brain neoplasia, which is characterised by significant resistance to conventional therapeutic modalities and a very particular immunosuppressive environment