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doi:10.1007/s12192-020-01168-z 718. Rodriguez-Ortiz CJ, Flores JC, Valenzuela JA, Rodriguez GJ, Zumkehr J, Tran DN, Kimonis VE, Kitazawa M

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& Deng, L

This oxidative insult has been demonstrated to impair pancreatic -cell function and exacerbate insulin resistance, thereby contributing to the progression of T2DM [310]