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Description

Excessive production of ROS not only directly damages cellular membranes, proteins, and DNA, but also activates inflammatory signaling pathways such as NF-B, thereby promoting the release of pro-inflammatory cytokines including TNF-, IL-1, and IL-6

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Shen Z, Hou Y, Zhao G, et al

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Cochrane Database Syst Rev (2013) 3):CD009594

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Individual cells tend to be round with pale basophilic cytoplasm and variably sized oval nuclei

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