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10.1093/brain/awx056 179 VickramS.RohiniK.SrinivasanS.VeenakumariD

The type III secretion chaperone HpaB controls the translocation of effector and non-effector proteins from Xanthomonas campestris pv

Furthermore, increased AMPK activity has been reported to increase translocation of GLUT4 to the membrane, increasing glucose uptake.61 In vitro studies using showed cardiomyocytes incubated with metformin showed increased AMPK activity as well as increased levels of glucose uptake.62 Overall, metformin may provide beneficial effects by restoring the metabolic shift in cardiomyocytes, which translates clinically into improved cardiac function in diabetic patients

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