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Similarly, the expression of HMGCR and SREBP1c were lower after simvastatin intervention in the liver and were closer to the levels in normal rats (113)

Interestingly, nanopore sequencing can also extract epigenetic status of the nucleotides (including both 5-Methylcytosine and 5-hydroxyMethylcytosine), and a large variety of bioinformatic tools have been developed for improving its detection properties