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Clarke, G

Results from recent published meta-analyses of observational studies are reported in Table 1 (adapted from 23)

Some promising compounds based on in vitro and in vivo testing fail during human clinical trials due to the species-specific differences in pharmacokinetics and toxicology [267]

From a preclinical viewpoint, additional research is needed to assess the neuroprotective agent in animals receiving long-term anti-autistic medication treatment