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The study, led by Astrup A and Madsbad S, involved obese subjects who received different doses of Tesofensine or a placebo for 24 weeks

Vitamin B12 supplementation significantly decreased serum levels of homocysteine compared to placebo (medians: 2.1 vs

deficiency (more common in those following plant-based diets or with malabsorption) can cause palpitations and fatigue, primarily through anaemia [2] [3] Vitamin D some observational studies have suggested a possible association between low vitamin D and cardiac arrhythmias, though the evidence remains preliminary and no causal link has been established [20] [21] Calcium severe hypocalcaemia can affect cardiac muscle function, though this is rarely caused by dietary restriction alone and usually reflects an underlying medical condition If you are concerned about nutritional deficiencies, your GP can arrange appropriate blood tests, which may include a full blood count (FBC), ferritin, vitamin B12 and folate, and urea and electrolytes (U&Es), with magnesium and calcium checked if clinically indicated

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