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Tsais lab has previously shown that MEF2 activation of these genes can confer resilience to cognitive impairment in the brains of people with Tau tangles, and she hypothesizes that the peptide treatment may have similar effects

All study types were considered given the limited clinical trial landscape

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In recreational athletes, supraphysiological GH doses are often used either alone or in combination with other doping substances (140), and studies have shown that GH improves anaerobic sprint capacity, but not strength and endurance (141), and increases GH, IGF-I and fasting insulin levels (142, 143) mimicking those seen in acromegaly patients ( Table 1 )