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Antioxidants (Basel) 11 (10), 2041

Interestingly, HGF also reduces a caspase-independent ischemic neuronal cell death by preventing apoptosis-inducing factor (AIF) translocation downstream of poly(ADP-ribose)polymerase 1 (PARP1) and p53 (Cregan et al., 2004

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Such inhibitors potentially have neuroprotective effects, improving cognition and memory by increasing synaptic plasticity and facilitating neurotransmission