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In cancer, inducers of ferroptosis, such as erastin and RSL3, take advantage of the high levels of iron and PUFAs in tumor cells [94, 95], while inhibitors like fer-1 and liproxstatin-1 show potential in treating neurodegenerative diseases, including Alzheimers, where lipid peroxidation contributes to neuronal damage [96]

After purification, His tag does not need to be removed because it has no effect on the function of the target protein

Similarly, GSH-activatable synthetic ion channels undergo GSH-mediated disassembly to release channel-forming compounds, leading to caspase-dependent apoptosis 217

Research shows a significant link between higher intimacy satisfaction scores and a lower likelihood of being diagnosed with mild cognitive impairment (MCI) or dementia over a 10-year follow-up period