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Notably, the fluorescence intensity of FA-rGO-BSA/AuNCs can be recovered in the presence of ascorbic acid with a concentration of 100 times higher than the amount of GSH (50 mM vs 0.5 mM of GSH)

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Adding guanfacine likely provides a potentiating synergistic benefit of activating the a2A-adrenergic receptors and increasing the postsynaptic signal in DLFPC Layer III pyramidal neurons