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10.1029/2019GL085117 32 BunzelK.SchferR

[ 219 ] A recent study reveals that the Keto diet leads to tumor metastasis by raising ATF4 levels, which interacts with BACH1 to enhance its transcriptional activation on prometastatic target promoters

I., Buchhalter, J

These ketone bodies (KB), including acetoacetic acid (acetoacetate), acetone and beta-hydroxybutyric acid (HB), can be utilized by the brain, heart and skeletal muscle through the citric acid cycle (Krebs cycle) and act as an energy source when glucose is not readily available (see Figure 1) (57)