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A higher dietary omega-6/omega-3 ratio, frequently observed in BD, has been linked to elevated peripheral inflammation [117,118] while higher levels of linoleic acid (LA) and other PUFAs appear to correlate with improved outcomes, including reduced depressive symptoms and fewer suicide attempts [60,119]

Trpv4 regulates Nlrp3 inflammasome via SIRT1/PGC-1alpha pathway in a cuprizone-induced mouse model of demyelination

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MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma