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Mn in bile is secreted into the small intestine, where it can either undergo enterohepatic recirculation or be eliminated via the feces by SLC30A10 located at the apical membrane of enterocytes

10.1136/gut.2008.164053

Following AILI, mitotic pressure drives midlobular hepatocytes into the pericentral zone, where they replace damaged cells

In addition to local treatment with HIF-PHIs, HIF-1-activated bone marrow-derived angiogenic cell infusion was also reported as an effective combination strategy in improving burn wound healing in aged mice (Du et al., 2013)