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What Are the Side Effects of IV Therapy

& FOWLER, C.A

Plasma glycine levels are close to the K m for glycine-gated chloride channels, so supplemental glycine, which can raise plasma glycine levels severalfold, tends to enhance the activity of these channels.29,30 Glycine is also a coagonist for certain neuronal N-methyl-D-aspartate (NMDA) channels.31,32 Additionally, glycine can suppress protein glycation and subsequent formation of advanced glycation end products by competing with protein-bound lysines for formation of Schiff bases with reactive aldehydes.33,34 In hepatocytes almost exclusively, glycine is metabolized to yield pyruvate (2 glycines generate 1 pyruvate)

Either fluorescence measurements or absorbance at 280 nm can be used