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Such practices in which mercury containing substances have traditionally been used include Santeria (a Cuban-based religion whose followers worship both African deities and Catholic saints), Voodoo (a Haitianbased set of beliefs and rituals), Palo Mayombe (a secret form of ancestor worship practiced mainly in the Caribbean), or Espiritismo (a spiritual belief system native to Puerto Rico)

Clinical studies show 20% to 30% improvement in skin firmness after twelve weeks of topical use

In addition numerous cytochromes of the oxidative-phosphorylation pathway contain heme