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doi: 10.1016/j.jaccas.2019.12.013 575 BenjaminEJBlahaMJChiuveSECushmanMDasSRDeoRet al

Regulations of enzymes critical for HBP and controlling high glucose-induced protein O-GlcNAcylation should be discussed

The soluble protofibrils formed from -synuclein exert their cytotoxicity through disruption of mitochondrial function, promotion of autophagy, lysosomal impairment and loss in regulation of calcium homeostasis (Van Laar et al., 2020), the two primary reasons accounting for loss in cellular homeostasis