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Moreover, BNIP3 and BNIP3L compete with Beclin-1 to bind to BCL2 and BCL-XL through their intrinsic BH3 atypical domain, resulting in disruption of the BCL2/BCL-XL-Beclin-1 complex and release of Beclin-1, which is required for autophagic activity [57]

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As global demand intensifies for minimally processed foods and clean-label technologies, the engineering of biopolymer nanoparticles represents a promising, safe, and eco-friendly approach to modern food preservation