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The study found that after IDH1 mutation, it will catalyze the massive conversion of 2-KG to tumor metabolite 2-HG, while consuming reduced NADPH

Now it has been 8 days since and it has not gone away nor become less warm, hard and itchy

Therefore, to regulate the metabolism of iron without affecting these important roles and affect ferroptosis and then treat tumors, a comprehensive understanding of its molecular mechanisms is required