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a source of heterogeneity and target for personalized therapy

Ingredients Bulking agent cellulose, L-glutathione reduced, carriers calcium phosphate and cross-linked sodium carboxymethyl cellulose, lactose monohydrate, pomegranate peel extract (Punica L.), superoxide dismutase, maltodextrin, milk thistle seed extract (Silybum marianum L.), L-cysteine, anti-caking agents magnesium salts of fatty acids and silicon dioxide, glazing agent (neutral methacrylate copolymer, talc, propylene glycol, colorant carmine)

Current platforms can only mediate single-base C-to-T or A-to-G conversions, leaving the majority of pathogenic variants unaddressed and offering no capacity for insertions, deletions, or larger-scale genomic modifications [555, 556]

10.3389/fcvm.2021.710963 62 HuX.RajeshM.ZhangJ.ZhouS.WangS.SunJ.et al (2018)