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Core functional layers of ferroptosis The heterocyclic trioxirane compound [1,3,5-tris((oxiran-2-yl)methyl)-1,3,5-triazinane-2,4,6-trione (TGIC)], recognized for its anticancer properties, is used as the core scaffold to conjugate a non-steroidal anti-inflammatory drug, yielding the novel compound BY1 [131]

To test this hypothesis, he employed click chemistry to label nascently synthesized proteins within cells in vivo (hat tip @CarolynBertozzi) Shockingly, he found that T cells were uniquely limited in their ability to synthesize proteins within tumors other cells within tumors synthesized proteins at higher rates, as did T cells within draining lymph nodes

The exclusion criteria included studies with insufficient or irrelevant information, as well as articles for which full-text versions were not accessible

Bedekovic et al., 2003