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doi: 10.3390/jcm9030846 185 DelauraIFGaoQAnwarIJAbrahamNKahanRHartwigMGet al

Hosseini H, et al

2020) and PD03A in PD patients and healthy controls have shown good safety and tolerability, as well as sustainable immunogenicity over time, and phase 2 trials are under way to test clinical efficacy

Monitoring mtDNA copy number, deletion frequency, and mutation load offers a window into cellular metabolic health, with potential as biomarkers for predicting ART toxicity, assessing immune reconstitution, and stratifying risk for neurological, cardiovascular, and age-related complications