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Lycium ruthenicum ethanol extract (LRE) mitigated colonic damage, restored immune homeostasis, and inhibited NLRP3 inflammasome assembly by suppressing MAPK activity in DSS (dextran sulfate sodium)-induced colitis mice (Zong et al., 2020)

25 Animal studies have shown that apoptosis of corporal smooth muscle cells, reduced nitric oxide synthase and PDE5 gene expression, which occur after castration, are reversed by testosterone administration