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This might occur in drugs that were approved prior to October 2018 when FDA issued guidance [279] regarding the selection of the appropriate package terms to address bacterial and viral infections among patients resulting from improper use of single-dose containers such as vials, ampules, and prefilled syringes

doi: 10.1016/j.bbadis.2009.08.008 22 VoroninaSGBarrowSLSimpsonAWMGerasimenkoOVXavierGDRutterGAet al

Moreover, the administration of these peptides to healthy individuals for anti-aging or performance enhancement introduces additional ethical and safety considerations, as the long-term effects of chronic exposure in otherwise healthy populations remain unknown