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Beyond energy production, NAD+ is also crucial for supporting DNA repair[1][2], regulating inflammation[2] and maintaining mitochondrial function[2]

In recent years, SAH has been found to be a high-efficient biomarker for the association between chronic kidney disease (CKD) and cardiovascular disease (CVD)

Future studies should focus on animal models to assess the pharmacokinetics of CBD derivatives and determine optimal dosing regimens

Disrupted cristae architecture also contributes to mitochondrial dysfunction, promoting electron leakage and superoxide formation, thereby amplifying mitochondrial ROS levels (43)