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In experimental studies, altering O-GlcNAc levels in the brain or cultured neurons reduces aberrant protein aggregation, which is a common hallmark of neurodegenerative diseases

Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, et al

RSL3 induced ferroptosis in a wide range of hepatocellular carcinoma cell lines, including all of them, and RSL3 could also enhance the sensitivity of tumors to ferroptosis in the presence of IFN- [170]