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Control groups of mice were maintained on LD or WD and given sham (10 mL/kg body weight sterile saline) injections throughout the study (termed LD/LD-V, or LD control, and WD/WD-V, or WD control, groups

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The original law was intended to make it easier for similar drugs to get FDA approval, but by removing the statement about chemically synthesized polypeptides at the 11th hour, it disenfranchised thousands of people from getting the medication they need