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Below pH 5, the amide stays protonated, the coordination geometry weakens, and copper(II) begins to dissociate as a free ion

doi: 10.1016/j.jfda.2014.10.012 57 SamadNHaleemDJ

Higher m is known to facilitate mitochondrial Ca 2+ uptake, activating bioenergetics by its effects on tricarboxylic acid (TCA) cycle dehydrogenases 9