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The evidence-based answer remains consistent: B12 injections deliver clear benefits for those with diagnosed deficiency and limited benefit for those with normal levels

Additionally, administration of IGF-1 in the presence of this antagonist results in a further improvement in insulin sensitivity

Methods Number of Prescriptions and Gross Spending Data: This analysis uses 2019 through 2024 State Drug Utilization Data (SDUD) (downloaded in January 2026)