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2024 Jul 13;81(1):299

The hydrolysis of drugs containing the amide group is very slow while the hydrolysis of the ester group is faster [8]

Functionalization strategies, green synthesis routes, and integration into composites further enhance its efficacy and safety profile

For instance, combining GPX4 inhibitors with chemotherapeutic agents or radiotherapy can enhance ROS accumulation and overwhelm cellular antioxidant defences ( Figure 4 ) (105107)