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In the present study, subcutaneous (s.c.) administration of reserpine at a dose of 1 mg/kg daily for 3 days was utilized

In animal models, it has been reported that the activation of apoptosis in type II AEC promotes a fibrotic phenotype, for example, apoptotic cells may release cytokines and growth factors that recruit and activate fibroblasts, prompting them to secrete ECM, whereas inhibiting apoptosis helps to alleviate pulmonary fibrosis (102104)

Impairments at any level of bilirubin metabolism or excretion can lead to hyperbilirubinemia and jaundice

De Vallire C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, et al