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Bound scFvs tagged with an N-terminal HA tag, were detected using an anti-HA antibody conjugated with horseradish peroxidase (HRP), followed by reaction with tetramethylbenzidine substrate (Thermo Fisher Scientific)

Ciriolo, Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

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For example, in male rats, it has been observed to ameliorate age-related deficits in memory and motor performance (Singh et al