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Indeed, conditions of overnutrition trigger inflammation and insulin resistance, along with elevated levels of inflammatory factors, such as circulating glucose and free fatty acids (FFA) ( Figure 1 )

Preclinical studies have shown that probiotic therapy confers specific immune responses in inflammatory cytokine expression, prevent cell apoptosis, and induce immunological memory against COVID-19 739

In an 8-week study on 23 OCD patients, zinc supplementation (as an add-on to fluoxetine) helped decrease obsessions and compulsions without causing adverse effects [65]

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