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This therapeutic gap necessitates exploration of alternative strategies targeting the underlying inflammatory drivers of disease progression

Pycnogenol is an extract of marine pine bark that includes procyanidins and phenolic acids (Packer 1999)

GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity

For example, in order to maintain intracellular redox homeostasis and build a powerful antioxidant defense, cancer cells are typically characterized by high level of antioxidants, especially GSH with a high concentration of 10 mM, which is approximately ten times higher than that in normal cells (Labarrere and Kassab, 2022)