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Organelle stress in the ER via the unfolded protein response (UPR) pathway and altered energy metabolism in mitochondria contribute to further damage to either organelle, causing various kidney disorders [2]

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There was partial or complete recovery from these lesions in the animals killed at the end of the recovery period

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Earlier, DJ-1/PfpI superfamily proteins were found to play important role in animal system under oxidative stress and mitochondrial dysfunction 18

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