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significantly enhanced fluorescence signals for MDA and 4-HNE measured in OA patient cartilage tissue by techniques like immunofluorescence staining (Shah et al., 2005)

In cell and animal models, amino acid metabolism not only provides substrates for energy production and biosynthesis, but also regulates the differentiation of macrophages toward M1 or M2 phenotypes by modulating signaling pathways such as STAT1, mechanistic target of rapamycin (mTOR), and NF-B, as well as by affecting epigenetic regulation (83)

Science 271 , 11261128 (1996)

Since the peptide is typically administered via subcutaneous injection, users may experience redness, swelling, or discomfort at the injection site