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[129-131] A phase I human trial found 6 g/day NAC completely protected against hematuria, which is a dose-limiting side effect of ifosfamide (an analogue of cyclophosphamide)

Biomarker assessment can reveal which individuals may be better candidates for peptide interventions

10.1093/aobpla/plv004 87 HasegawaP

The two allelic variants HET-s and HET-S differ at only 13 amino acids positions and share the same domain architecture with an N-terminal globular HeLo domain and an unstructured C-terminal prion-forming domain (PFD) (Figure 4A) formed by HET-s(218289) has been solved by SSNMR (Figures 4B,C) by Wasmer et al