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The significance of neovascularization, inflammation, and apoptosis might imply that HO-1 plays a role in governing the process of wound healing [115]

Reported benefits (per available research): Studied for its ability to raise GH and IGF-1 toward youthful levels and blunt age-related loss of fat-free mass, based on a 2-year randomized, placebo-controlled trial in 65 healthy older adults (Nass et al., 2008, Annals of Internal Medicine, PMID 18981485)

Interestingly, some C-type lectin from snake venom such as rhodocytin (also termed aggretin) purified from the venom of Calloselasma rhodostoma bind to CTLD domain of CLEC-2

However, veterinary research on CUP, particularly in cats, is limited, with few reported cases