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doi: 10.1016/j.critrevonc.2021.103461 61 HovattaOSilyeRKrauszTAbirRMargaraRTrewGet al

However, increased intestinal permeability can promote translocation of luminal bacteria and microbial-associated molecular patterns, in particular, lipopolysaccharides (LPS) from the gut into bloodstream, triggering the development of endotoxemia and chronic low-intensity inflammation (Vanuytsel et al., 2021)

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Control mice received the same daily volume of DMSO subcutaneously