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The study included 517 patients with PCOS who ceased metformin treatment upon confirmation of pregnancy, with a recorded birth defect rate of 0.6%

On the other hand, preclinical studies and clinical trials highlight the potent anti-inflammatory effects of TB-500 in various models of organ and tissue injury, including in the skin, eye cornea, liver, and central nervous system [34, 35, 38, 39]

AGA clinical practice update on chemoprevention for colorectal neoplasia: expert review

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