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doi: 10.3389/fenvs.2014.00053 31 DatJ.VandenabeeleS.VranovE.Van MontaguM.Inz*D.Van BreusegemF

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The same enzymes designed to break down dietary protein into amino acids

Drugs such as amsacrine, etoposide, and doxorubicin target topoisomerase type II (type II), while cytotoxic alkaloids and camptothecin (CPT) are recognized as inhibitors of type I [74]